TNNI2 monoclonal antibody, clone 2F12A8
产品名称: TNNI2 monoclonal antibody, clone 2F12A8
英文名称: TNNI2 monoclonal antibody, clone 2F12A8
产品编号: MAB10338
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant TNNI2.
- Immunogen:
- Recombinant protein corresponding to human TNNI2.
- Host:
- Mouse
- Theoretical MW (kDa):
- 21
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis using TNNI2 monoclonal antobody, clone 2F12A8 (Cat # MAB10338) against HEK293 (1) and TNNI2-hIgGFc transfected HEK293 (2) cell lysate.
- Western Blot (Recombinant protein)
- Western blot analysis using TNNI2 monoclonal antobody, clone 2F12A8 (Cat # MAB10338) against recombinant human TNNI2 protein.
- Entrez GeneID:
- 7136
- Gene Name:
- TNNI2
- Gene Alias:
- AMCD2B,DA2B,FSSV
- Gene Description:
- troponin I type 2 (skeletal, fast)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000014141,OTTHUMP00000014142,troponin I fast twitch 2,troponin I, fast-twitch skeletal muscle isoform,troponin I, skeletal, fast
- Related Disease