PTGER4 polyclonal antibody
产品名称： PTGER4 polyclonal antibody
英文名称： PTGER4 polyclonal antibody
产品编号： PAB6969
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of PTGER4.
- Immunogen:
- A synthetic peptide corresponding to human PTGER4.
- Sequence:
- C-LEREVSKNPDLQA
- Host:
- Goat
- Theoretical MW (kDa):
- 53.1
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:16000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Stimulation of PGE receptors EP2 and EP4 protects cultured neurons against oxidative stress and cell death following beta-amyloid exposure.
Echeverria V, Clerman A, Dore S.Eur J Neurosci. 2005 Nov;22(9):2199-206.
- Entrez GeneID:
- 5734
- Protein Accession#:
- NP_000949.1
- Gene Name:
- PTGER4
- Gene Alias:
- EP4,EP4R,MGC126583
- Gene Description:
- prostaglandin E receptor 4 (subtype EP4)
- Omim ID:
- 601586
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq
- Other Designations:
- PGE receptor, EP4 subtype,prostaglandin E receptor 4, subtype EP4,prostaglandin E2 receptor
- Gene Pathway
- Related Disease
- Adenoma
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Bipolar Disorder
- Cardiovascular Diseases
- Chorioamnionitis
- Colorectal Neoplasms
- Coronary Artery Disease
- Crohn Disease
- Diabetes Complications
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Ductus Arteriosus, Patent
- Edema
- Fetal Membranes, Premature Rupture
- Genetic Predisposition to Disease