MAPK10 monoclonal antibody, clone 2G12H3
产品名称： MAPK10 monoclonal antibody, clone 2G12H3
英文名称： MAPK10 monoclonal antibody, clone 2G12H3
产品编号： MAB5533
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant MAPK10.
- Immunogen:
- Recombinant protein corresponding to human MAPK10.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Role of mitogen- and stress-activated kinases in ischemic injury.
Irving EA, Bamford M.J Cereb Blood Flow Metab. 2002 Jun;22(6):631-47.
- 2.
- Mitogen-activated protein kinase kinase 4 (MKK4).
Cuenda A.Int J Biochem Cell Biol. 2000 Jun;32(6):581-7.
- 3.
- The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.
Kuan CY, Yang DD, Samanta Roy DR, Davis RJ, Rakic P, Flavell RA.Neuron. 1999 Apr;22(4):667-76.
- Entrez GeneID:
- 5602
- Gene Name:
- MAPK10
- Gene Alias:
- FLJ12099,FLJ33785,JNK3,JNK3A,MGC50974,PRKM10,p493F12,p54bSAPK
- Gene Description:
- mitogen-activated protein kinase 10
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
- Other Designations:
- JNK3 alpha protein kinase,MAP kinase,OTTHUMP00000161180,OTTHUMP00000161182,OTTHUMP00000161183,c-Jun N-terminal kinase 3,c-Jun kinase 3,stress activated protein kinase JNK3,stress activated protein kinase beta
- Gene Pathway
- Adipocytokine signaling pathway
- Colorectal cancer
- Epithelial cell signaling in Helicobacter pylori infection
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Focal adhesion
- GnRH signaling pathway
- Insulin signaling pathway
- MAPK signaling pathway
- Neurotrophin signaling pathway
- Pancreatic cancer
- Pathways in cancer
- Toll-like receptor signaling pathway
- Type II diabetes mellitus
- Wnt signaling pathway
- Related Disease