ROCK1 Polyclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司
ROCK1 Polyclonal Antibody

ROCK1 Polyclonal Antibody

商家询价

产品名称: ROCK1 Polyclonal Antibody

英文名称: ROCK1 Polyclonal Antibody

产品编号: K001838P

产品价格: null

产品产地: 北京市通州区马驹桥联

品牌商标: solarbio

更新时间: 2025-02-08T13:37:52

使用范围:

北京索莱宝科技有限公司
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Anti-ROCK1 Polyclonal Antibody

品牌:solarbio | 货号:K001838P
商品货号:商品品牌:规格基本售价:选择规格
K001838P-50ulsolarbio50ul960.00元
K001838P-100ulsolarbio100ul1600.00元
英文名称Anti-ROCK1 Polyclonal Antibody
别名P160ROCK;ROCK-I
应用WB IHC IP
稀释比例WB 1:500-2000. IHC 1:50-100. IP 1:50-100.
交叉反应Human Mouse Rat
蛋白分子量158kDa
Gene ID6093
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human ROCK1
性状液体
Public Immunogen RangeRecombinant protein of human ROCK1
Subcellular LocationsCell membrane Cell projection Cytoplasm Golgi apparatus membrane Peripheral membrane protein bleb centriole centrosome cytoskeleton lamellipodium microtubule organizing center ruffle
Swiss ProtQ13464
克隆类型Polyclonal Antibody
背景资料This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18.